Daily Digest.

The Ataxias as an Example of Rare Diseases: Diagnosis, Genetics, and Treatment

Erdlenbruch F, Thieme A, Depienne C et al. · Dtsch Arztebl Int

The Value of Ataxia Centres – The Value of Treatment project

Ataxia UK

RFC1 Repeat Distribution in the Cypriot Population - Neurology® Journals

Neurology® Journals

RFC1-Related Disorders

Adam MP, Bick S, Mirzaa GM et al.

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS neurons - Science | AAAS

Science | AAAS

Gluten Ataxia in Children and adolescents – A study of patients at the Sheffield Paediatric Ataxia Centre

Ataxia UK

Cramps as the initial presentation of CANVAS/RFC1-related disorder

Machado J, Zwicker J, Bourque PR et al. · J Neuromuscul Dis

Distinct small-fiber dysfunction profiles in CMT1A and RFC1 disease: a multimodal study

Massucco S, Leandri M, Bruzzone V et al. · J Neurol

PTC Therapeutics Updates Page

Ataxia UK

Characteristics of a Cohort of Individuals With SCA27B Associated With Repeat Expansions in FGF14

Anderson SC, Patel SG, Rodrigues M et al. · Neurol Genet

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies - Fogel - 2025 - Annals of Neurology - Wiley Online Library

Wiley Online Library

Another good day in the fight for Skyclarys by Clare Sheeran

Ataxia UK

All About Ataxia November 2026

Ataxia UK

RFC1 regulates the expansion of neural progenitors in the developing zebrafish cerebellum - Nature

Nature

Blank Canvas Syndrome

MDS

Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis - National Institutes of Health (NIH) | (.gov)

National Institutes of Health (NIH) | (.gov)

Meet Nathan Lee Davies

Ataxia UK

Concerts and Holidays by Clare Sheeran

Ataxia UK

Oligodendrocyte Models of Spastic Ataxia 8 for Remyelination (OLYSPAX8)

Ataxia UK

[CANVAS and RFC1-related disease - a broad clinical spectrum from cough and neuropathy to cerebellar ataxia]

Andrén K, Paucar M, Thonberg H · Lakartidningen

Q&A: Fay Grant On Bringing Her Entrepreneur Spirit To Fighting RFC1-CANVAS - Forbes

Forbes

An Update on the Adult-Onset Hereditary Cerebellar Ataxias: Novel Genetic Causes and New Diagnostic Approaches - SpringerMedizin.de

SpringerMedizin.de

Early Peripheral Nerve Involvement at the Time of Coughing in Patients With RFC1 Intronic Expansion - Neurology® Journals

Neurology® Journals

Remote Monitoring of SCA3 Symptoms

Ataxia UK

Ataxia UK-funded research shows that targeting sphingolipids protects cells from damage in cell and mouse models of FA

Ataxia UK

impact-pr/eSCA – An Intensive, Motor, Personalized, Anywhere, and Challenging Training for Pre- and Early-Ataxic Spino-Cerebellar Ataxia Patients

Ataxia UK

Shoes by Clare Sheeran

Ataxia UK

CANVAS (Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome)

Vestibular Disorders Association

CANVAS- (ICU - "I See You" Podcast Ep 41)

Vestibular Disorders Association

RFC1-CANVAS Spectrum Disorder: A Story of Hope

RFC1 CANVAS Spectrum Disorder Awareness Channel